That wish to become augmented. To have the addition of genetic modifications, cyborg appliances, and aid the evolutionary process beyond that which Darwin covered so long ago.
While I'm sure there will be a lot in the way of advancements in immunology, genetics, neurology, and most certainly metabolism and other aspects of the living human ... something about genetic editing and the subsequent products are quite the disturbing thought for me personally.
Heck, I won't even (knowingly) eat GMO type foods. That test tube steak they just cooked up recently didn't ever stand a chance landing on my plate.
I just feel there are appropriate venues for meddling with configuations and my food simply isn't one of them.
This is not to say that I wouldn't undergo some genetic editing if I thought there were significant gains to be had.
Unlike the technologists and transhumanists of our era I simply cannot call these interventions in our biological processes "investment in the future".
Surely the life expectancy would have gone up instead of taking the rather precipitous drop it has in the United States of late.
Then you have the ridiculous brigand Obama who single handedly ruined The Republic with that poof he married and now wishes to divorce ... all the while trying to take credit for the successes of the next administration.
We need to avoid more errors of judgement like electing these libtards and progressives. I view some of the things on the agenda of transhumanist progression to be similarly bad for people in general.
We certainly could get the 'natural' person more correct prior to modifying some damaged goods in the name of repairs or augmentation.